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Cancel Continue. Arthritis is an umbrella term covering over conditions that affect the joints, tissues around the joint and other connective tissues. In a broad definition, arthritis means inflammation or swelling of one or more joints. A diagnosis of arthritis is often due to acute or chronic inflammation of a joint, which is often accompanied by pain and structural changes.
The specific causes of arthritis are unknown, but may be triggered by infection, crystal deposition, genetics, injury or repetitive use. Specific symptoms vary depending on the type of arthritis, but usually include joint pain and stiffness. For information about a specific type of arthritis, click on one of the most prevalent forms below. The Foundation will continue to update this page with more information and cover as many types of arthritis as possible.
We are committed to finding new treatments and cures to help all of the individuals suffering. Rheumatoid Arthritis. Ankylosing Spondylitis. Non-radiographic Axial Spondyloarthritis explained.
A Young Woman's Journey. Psoriatic Arthritis. Be Quick. Giant Cell Arteritis. Self-injecting methotrexate. What is My Health Record? Your stories. Get involved. Make a donation. Workplace giving. Donate to research. Keep up-to-date. Partner with us. Share your WrapRage. Position statements. Accessible Design Division. National Research Program. Our grants. Why invest in research.
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A healthy immune system is protective. It generates internal inflammation to get rid of infection and prevent disease.
But the immune system can go awry, mistakenly attacking the joints with uncontrolled inflammation, potentially causing joint damage and may harm internal organs, eyes and other parts of the body. This makes RA an autoimmune disease as the immune system primarily goes after the lining of the joints, called the synovium. Over time, the persistent inflammation breaks down the joint and damages it permanently, if remains untreated.
Psoriatic arthritis PsA is an autoimmune inflammatory disease in which the immune system attacks the body, causing inflammation and pain. PsA affects the body in three ways; joints, causing arthritis; the connective tissue where tendons or ligaments attach to bones, causing enthesitis; and the skin, causing psoriasis.
Another autoimmune inflammatory disease is lupus. It affects many parts of the body including the joints, kidneys, skin, blood, brain and other organs. It can cause joint pain, fatigue, hair loss, skin sensitivity to light, fever, rash and kidney problems.
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