Another review came to the same conclusion. Short-acting statins work better at night because the liver enzyme that produces cholesterol is more active at this time. Most short-acting statins have a half-life of 6 hours. It takes longer for the body to process long-acting statins, which may have a half-life of up to 19 hours. The two reviews above noted that long-acting statins worked equally well whether a person took them in the morning or the evening. Therefore, people taking long-acting statins can choose which time of the day best suits them.
The authors recommend that people using long-acting statins take them at a time of day that is easy for them to remember. It is important to be consistent with the timing of doses, so if a person prefers to take statins in the morning, they should take them in the morning every day.
People who are taking statins may need to take them indefinitely. In many cases, when a person stops taking statins, their cholesterol levels increase again. Some people might be able to stop taking statins or reduce their dosage if they significantly lower their risk of heart disease. A person may do this by losing a significant amount of weight, quitting smoking , or making other major lifestyle changes that improve their health. Even in these cases though, a person should talk to a doctor before they stop taking statins or any other medications.
Statins come in a range of types and dosages. A person can discuss with their doctor which type of statin may work best for them. If a person has an increased risk of heart disease, their doctor may prescribe a higher dosage or a long-acting statin. Conversely, a person with less risk of heart disease may start on a lower dosage or a short-acting statin. Recent evidence suggests that many people can benefit from taking statins, even if they do not have high blood cholesterol levels.
The American Heart Association say that statins can benefit people who have an average risk of heart disease, especially when they take them in combination with medications to lower blood pressure.
Statins do not cause serious side effects for most people. According to the American College of Cardiology , as many as 90 percent of people taking statins do not experience bothersome side effects. For those who do experience side effects, these may include:. The Food and Drug Administration FDA state that the risk of these side effects is small and that the benefits of statins usually outweigh this risk.
Some reports have warned that statins can cause severe memory loss, but an investigation found inconsistent evidence of this side effect. Another review states that there is evidence to suggest that statins do not affect memory. In rare cases, a person taking statins may have serious side effects, such as liver damage or an allergic reaction. The following side effects require immediate medical attention:.
Statins can interact with some medications. People who take statins will need to make their doctor aware of any medicines, vitamins , herbs, or other supplements that they take to help prevent dangerous interactions. Statins may also interact with grapefruit and grapefruit juice. Therefore, it is important to avoid eating grapefruit or drinking grapefruit juice while taking statins unless a doctor says it is safe.
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Fewer than one-third of adults Find out why. Read more. Your doctor should do blood tests to check your liver before starting treatment and if you have symptoms of liver problems while taking CRESTOR Call your doctor right away if you: Have unexplained muscle pain or weakness, especially with fever Have muscle problems that do not go away even after your doctor told you to stop taking CRESTOR Feel unusually tired Have loss of appetite, upper belly pain, dark urine, or yellowing of skin or eyes These could be signs of rare but serious side effects Elevated blood sugar levels have been reported with statins, including CRESTOR Side effects: The most common side effects may include headache, muscle aches, abdominal pain, weakness, and nausea.
Efficacy and tolerability of rosuvastatin and atorvastatin when force-titrated in patients with primary hypercholesterolemia: results from the ECLIPSE Study. You are leaving this site The site you are about to visit is maintained by a third party who is solely responsible for its contents.
Rosuvastatin is also called by the brand name Cresto. Rosuvastatin can be taken by adults and children over the age of 6 years.
Tell your doctor if you: have had an allergic reaction to rosuvastatin or any other medicines in the past have liver or kidney problems are trying to get pregnant, think you might be pregnant, are already pregnant or are breastfeeding have severe lung disease take a medicine called ciclosporin or a close relative has or have had a muscle disorder including fibromyalgia Rosuvastatin also comes as a higher 40mg dose for adults.
Tell your doctor if you also: have an underactive thyroid have had problems with your muscles when taking a statin or another cholesterol lowering medicine in the past regularly drink large amounts of alcohol are of Asian origin take other medicines called fibrates to lower your cholesterol. Swallow rosuvastatin tablets whole with a glass of water. How much to take How much you take depends on what you're taking rosuvastatin for: preventing heart attacks and strokes - the usual dose for adults is 20mg once a day.
Sometimes a lower dose may be prescribed. If needed, your doctor may increase your dose every 4 weeks up to 20mg a day. The maximum dose for children is 20mg a day. Do not reduce your dose without talking to your doctor first. What if I forget to take it? If you forget doses often, it may help to set an alarm to remind you. What if I take too much? Urgent advice: Call your doctor straight away if you take too much rosuvastatin.
Common side effects These side effects happen in more than 1 in people. Keep taking the medicine, but tell your doctor or pharmacist if these side effects bother you or do not go away: feeling sick headaches stomach pain feeling weak or dizzy constipation protein in your pee if you're taking the higher 40mg dose - your doctor will check for this as there are no symptoms for this side effect Serious side effects Serious side effects are rare and happen in less than 1 in 1, people. Stop taking rosuvastatin and call a doctor if you get: muscle pain, tenderness, weakness or cramps - these can be signs of muscle breakdown and kidney damage yellow skin or the whites of your eyes turn yellow - these can be signs of liver problems severe stomach pain - this can be a sign of pancreas problems a cough, shortness of breath and weight loss - these can be signs of lung disease Less than 1 in 10, people may experience memory loss.
Do not stop taking the medicine without talking to your doctor first. Serious allergic reaction In rare cases, it's possible to have a serious allergic reaction anaphylaxis to rosuvastatin. These are not all the side effects of rosuvastatin. For a full list, see the leaflet inside your medicines packet. Information: You can report any suspected side effect to the UK safety scheme. What to do about: feeling sick - stick to simple meals and do not eat rich or spicy food.
It might help to take your rosuvastatin after a meal or snack. Contact your doctor if your symptoms continue for more than a few days or get worse. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Talk to your doctor if they last longer than a week or are severe. It can help to eat and drink slowly and have smaller and more frequent meals. Putting a heat pad or covered hot water bottle on your tummy may also help.
If you're in a lot of pain, speak to your pharmacist or doctor. Do not drive or use tools or machinery if you're feeling tired. Do not drink alcohol as it'll make you feel worse.
Try to exercise more regularly, for example, by going for a daily walk or run. If this does not help, talk to your pharmacist or doctor. Watch this short video about how to treat constipation. Your doctor may want to monitor you to check this happens. Rosuvastatin and breastfeeding It's not known if rosuvastatin passes into breast milk, but it may cause problems for your baby.
Non-urgent advice: Tell your doctor if you're:. Tell your doctor if you're taking: antibiotics, such as erythromycin some antiviral medicines used to treat infections, such as HIV and hepatitis medicine for indigestion, such as Gaviscon blood-thinning medicines, such as clopidogrel and warfarin ciclosporin, used to treat psoriasis and rheumatoid arthritis contraceptive pills and hormone replacement therapy other medications used to lower cholesterol If you're taking rosuvastatin and need to take one of these medicines, your doctor may lower your dose or prescribe a different statin.
These are not all the medicines that can interfere with rosuvastatin. Mixing rosuvastatin with herbal remedies and supplements There's very little information about taking herbal remedies and supplements while you use rosuvastatin. Important For safety, tell your doctor and pharmacist if you're taking any other medicines, including herbal remedies, vitamins or supplements. How does rosuvastatin work? How long does rosuvastatin take to work?
How long will I take rosuvastatin for? Is it safe to take rosuvastatin for a long time? Rosuvastatin is safe to take for a long time, even many years. In fact, it works best when you take it for a long time. Are statins safe? What will happen if I stop taking it?
Is rosuvastatin addictive? No, there's no evidence that rosuvastatin is addictive. You will not get any withdrawal symptoms when you stop taking it. How does it compare with other statins? There are several other statin medicines, including: atorvastatin fluvastatin pravastatin simvastatin Statins all work in the same way, but they differ in how well they lower cholesterol.
Will taking rosuvastatin increase my risk of diabetes?
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